Yes, iS3 ANTIvirus can protect systems running both the 32-bit and 64-bit versions of Vista. Installation is the same as on other Windows operating systems.
It is recommended that Vista users disable the "User Account Control" feature prior to installation, and re-enable it after installation.
To disable User Account Control:
- Click Start in the lower left corner of your screen.
- From the Start menu, select Control Panel > User Accounts > Enable/disable.